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Die Strategische Area forscht an neuen, bahnbrechenden Ansätzen in Forschungsfeldern, in denen das acib eine besonders starke Expertise entwickelt hat. Diese Forschungskernthemen beziehen sich auf Proteine und Bio-Nanopartikel, Mechanismen der phenotypischen Kontrolle in Zellfabriken und Multi-enzymatische biokatalytische Kaskadenreaktionen. Zusätzlich treibt die Strategische Area aufstrebende Forschungsthemen voran und unterstützt neue, innovative Ideen junger ForscherInnen.
Die Area Biotransformationen beschäftigt sich mit neuen Enzymen und flexiblen biokatalytischen Prozesstechnologien für eine effiziente, kontinuierliche chemische Produktion. Das Ziel ist es, neue, robuste Biotransformationsprozesse, insbesondere für Glykosylierungen, oxidative C-H Funktionalisierungen und enzymatische Kaskadenreaktionen.
Die Area drei fokussiert sich auf mikrobielle Zellen und deren Werkzeuge. Mit Hilfe von Methoden der Synthetischen Biologie werden neue Funktionen und eine effiziente Bioproduktion kleinster Moleküle und Proteine ermöglicht. Weiters wird an der Nutzung mikrobielle Gemeinschaften im Bereich industrieller Applikationen geforscht.
Angelehnt an die Vision der “Virtuellen Fabrik” und des “Digitalen Zwillings” konzentriert sich die Area 4 auf die Entwicklung und Validierung von vielschichtigen Methoden in der gesamten Herstellungskette. Dies führt zu einer effizienteren, verlässlicheren und besser kontrollierbaren Produktion und Verarbeitung von hochqualitativen, sicheren Biopharmazeutika und Diagnostika.
In bridging the gap between industry and academia, acib provides unique career chances. Either your career path leads you to academia, industry or acib – join us and keep all doors widely open!
Being located in Austria, acib benefits from the unique Austrian culture. A perfect balance between professionality and social greatness. And a great place to live and work.
By offering flexibility in organising your daily work, acib supports the reconciliation of work and private life in the best way possible. This might not be unique. But we are aware that your private circumstances are. We do our best to fit into your life, let’s match!
Our expertise and professionality are right here to support you. Our guidance through the visa process lets you arrive in Austria very quickly. A structured onboarding process enables you to feel safe and sound as a new acib team member.
Biokatalyse
In diesem Forschungsbereich geht es um den Einsatz von Biokatalysatoren für die Umwandlung und Synthese von Molekülen und die Ersetzung herkömmlicher chemischer Verfahren durch effiziente und umweltfreundliche Ansätze.
Kontakt: Prof. Robert Kourist
Mikrobielle Biotechnologie
Das Forschungsgebiet umfasst die biotechnologische Nutzung von Mikroorganismen (Bakterien, Hefen, Pilze) und deren Kompartimenten zur Herstellung von Proteinen oder wichtigen Stoffwechselprodukten.
Kontakt: Prof. Diethard Mattanovich
Enzymtechnologien
In diesem Forschungsbereich beschäftigen wir uns mit neuen enzymatischen Umsetzungen in synthetischen Ansätzen, um aktuelle Lücken in der Anwendung enzymatischer Prozesse zu schließen, sowie mit der Immobilisierung von Enzymen.
Kontakt: Prof. Bernd Nidetzky
Protein Engineering
Wir kombinieren direkte Laborevolution mit strukturbasiertem rationalem Design, um die Aktivität, Stabilität, Affinität, Löslichkeit oder Expression von Proteinen - von Enzymen bis hin zu Biotherapeutika - zu optimieren.
Kontakt: Prof. Bernd Nidetzky
Zelllinienentwicklung & Epigenetik
Die in diesem Bereich durchgeführten Projekte befassen sich mit einem detaillierten, molekularen Verständnis der Eigenschaften von Produktionszelllinien (z.B. CHO), die für die Herstellung von biopharmazeutischen Produkten verwendet werden.
Kontakt: Prof. Nicole Borth
Bioinformatik & Simulationen
Gene, RNA, Proteine und Metaboliten sind die Hauptakteure in biologischen Systemen. Die Summe dieser Teile ist weniger als das Ganze, denn diese Akteure handeln nie allein, sondern sind in komplexe und vielschichtige Netzwerke eingebunden.
Kontakt: Prof. Jürgen Zanghellini
Bioprozesstechnologien
Der Forschungsbereich Bioprozesstechnologien befasst sich mit der Entwicklung verbesserter oder neuer biotechnologischer (kontinuierlicher) Prozesse, flexibler Produktion und Prozessintensivierung sowie mit prozessanalytischen Technologien.
Kontakt: Prof. Alois Jungbauer
Umweltbiotechnologie & Bioökonomie
Recycling und die Wiederverwertung von Abfällen ist ein wichtiges Zukunftsthema. Vom Abbau natürlicher und synthetischer Polymere bis zur Biolaugung und Aufwertung von Abfallströmen ist acib weltweit führend auf zahlreichen Gebieten der Bioökonomie.
Kontakt: Prof. Georg Gübitz
Benefits
- Network & Public Relations: Access to an extensive industrial network for applied research in the field of industrial biotechnology
- Efficiency: By using services such as management, marketing, IP management, etc., researchers can focus on what they do best, namely science
- Independence: Independent, not-for-profit research center that can take advantage of funding programs that universities cannot
- Transparency: You are always visible as the main person in charge of your project and receive information about the current status and offers at any time
- Confidentiality: After the initial one-pager with non-confidential information as a teaser to generate interest, we provide CDA/NDAs to protect your idea before we have detailed discussions
- Frictionless: easy project management, non-bureaucratic cooperation (through legal framework), professional project management and marketing
- Central contact point for industrial research: Access to infrastructure of university partners and key researcher know-how
- We bundle individual competencies to comprehensive solutions
- We create customized solutions for industrial research questions and requirements
- Exchange & synergy through our network: Interdisciplinarity and coverage of the entire development and process chain
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acib assists you with your application. All required documents, such as the hosting agreement, will be provided by us as soon as possible to ensure a smooth visa process. The following links provide further information:
Interested in becoming a part of acib?
- Step 1: Application
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- Step 4: Job interviews
- Step 5: Decision
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The strategic area breaks new scientific ground within CORE themes of the Centre’s research. This CORE topics are proteins and bio-nanoparticles at surfaces, mecha- nisms of phenotypic control in cell factories and multi-enzyme biocatalytic cascades. Moreover, the area boosts emerging research topics and fosters new ideas from young scientists. The strategic area paves the way for new collaborations with industry including future individual projects in COMET thus expanding the total research portfolio of acib.
The area focuses on new enzymes and flexible biocatalytic process technologies for efficient, continuous chemical production. The objective is to develop new, robust biotransformation processes, in particular for glycosylation, oxidative C-H functionalization and enzyme cascade reactions. Aims are marked cost reduction by modularization, increase of flexibility and shortening of development timelines and thus time to market for biocatalytic processes and products. Furthermore, the scope of biocatalytic processes will be expanded.
The area is focused on microbial cells and their parts designed by synthetic biology for new functions and efficient bioproduction of small molecules and proteins. It furthermore breaks new ground in harnessing microbial communities for industrial applications. Chassis strains and new hosts increase yields, productivities and titers resulting in substantial financial savings. Modularization by synthetic biology concepts reduces development times.
Guided by the vision of the “virtual factory / digital twin” the area focus is on the development and validation of multi-level models of the entire development and manufacturing chain for the efficient, reliable and controllable production and processing of high quality and safe biopharmaceuticals and diagnostics. Marked cost reducing factors are shorter development times and thus shorter times to market, reduced screening and development efforts, reduction of batch failures and streamlining of manufacturing schedules. An important beneficial consequence of such robust production processes is the avoidance of drug shortages. Site-independent training using virtual factory modules additionally offers striking economic benefits.
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Research for a better world
acib’s vision is a world without suffering and with affordable access to food and medicine for all the people on this world. acib’s mission is
Aktuelle Technologie- & Serviceoffers (Englisch)
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