Bionanoparticles, i.e. viruses, virus-like particles (VLP) or extra-cellular particles such as exosomes, are the next generation of biopharmaceuticals used for vaccines, gene therapy and immunotherapy. Bottleneck in rapid development of these advanced medicines are the lack of under- standing of the process mechanisms, best choice of process units and scale-up of up- and downstream production processes, as well as the lack of high-throughput analytical tools for bionanoparticle detection and identification in complex mixtures.
At acib, in collaboration with BOKU, we established a full set of instruments and expertise to develop integrated bioprocessing and analytical methods for generation of process understanding and characterization of bionanoparticle production and purification. Sophisticated infrastructure is established in a BSL2 facility at acib/BOKU which can be made available to partners in collaborative projects and also to external users.
Experts:Prof. Dr. Alois Jungbauer, Dr. Gerald Striedner, Dr. Patricia Pereira Aguilar Dr. Peter Satzer, Dr. Verena Beck
Joint Research Projects