A purification process for vaccines produced via a measles vector platform will soon lead to a more flexible, reproductive and economic process contributing to the faster development and production of vaccines.

mRNA vaccines gained widespread notoriety for their revolutionary power in combating the Corona pandemic. But behind the scenes, a silent hero called pseudouridine plays a crucial role in maximising their efficacy and safety. Pseudouridine, a modified RNA building block, has the remarkable ability to increase RNA stability and fine-tune immune responses, making it a valued component in the world of mRNA therapeutics. However, with the increasing demand for these breakthrough vaccines, the question arises: how can we produce pseudouridine sustainably without compromising efficiency or environmental impact?

Living fossils allow us a glimpse into a time long past, for they have changed little or not at all over millions of years. The platypus or the horseshoe crabs are well-known representatives from the world of animals; among plants, horsetail, ginkgo or the box tree are considered such living fossils. But the world of microorganisms can also come up with living fossils: the so-called archaea are a special group of microorganisms, which are characterised by a special composition of the cytoplasmic membrane and sometimes also through specific cell envelope that is not found in bacteria or eukaryotic organisms…