A purification process for vaccines produced via a measles vector platform will soon lead to a more flexible, reproductive and economic process contributing to the faster development and production of vaccines.
mRNA vaccines gained widespread notoriety for their revolutionary power in combating the Corona pandemic. But behind the scenes, a silent hero called pseudouridine plays a crucial role in maximising their efficacy and safety. Pseudouridine, a modified RNA building block, has the remarkable ability to increase RNA stability and fine-tune immune responses, making it a valued component in the world of mRNA therapeutics. However, with the increasing demand for these breakthrough vaccines, the question arises: how can we produce pseudouridine sustainably without compromising efficiency or environmental impact?
Living fossils allow us a glimpse into a time long past, for they have changed little or not at all over millions of years. The platypus or the horseshoe crabs are well-known representatives from the world of animals; among plants, horsetail, ginkgo or the box tree are considered such living fossils. But the world of microorganisms can also come up with living fossils: the so-called archaea are a special group of microorganisms, which are characterised by a special composition of the cytoplasmic membrane and sometimes also through specific cell envelope that is not found in bacteria or eukaryotic organisms…
A Europe-wide project named “Piezo4Spine” sets the high goal of developing a novel therapy against spinal cord injuries (SCI). Based on the latest findings in materials science, regenerative medicine and nanotechnology, research is being conducted on a 3D-theramesh equipped with bioactive nanocarriers that delivers therapeutic agents to the site of the lesion through electrical stimulation. These bioactive ingredients activate the neuronal regeneration processes after an SCI has occurred. If successful, this technology could be useful in the future for pathologies such as Alzheimer’s or Parkinson’s disease, among others.
Opiate alkaloids such as morphine and codeine are important pharmaceutical ingredients used to treat severe pain. Morphine is even classified as an essential medicine by the World Health Organization (WHO). Opiate-based medications are crucial to provide normal life for patients who need long-term pain management due to living with terminal cancer, sickle cell disease, COPD- related dyspnea, (etc.). Unfortunately, morphine is practically unavailable in low- and middle-income countries leaving patients in suffering.
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acib has a leading experience in industrial bioprocess design for enzymatic glycosylation reactions and is actively looking for new company collaborations interested in our glycosylation know-how.
acib developed a biotechnological based technology for the recycling of waste pharmaceutical blisters. Aluminium and plastic can be recovered by applying the concept of green chemistry.
Wastewater-based detection of emerging diseases has been proven to be a powerful tool during the COVID-19 pandemic. Now it’s high time to switch from a time-consuming manual and decentralized process to a fully-automated multiple-disease detection and surveillance system.
The pharmaceutical industry has had to resort to rather inefficient, environmentally harmful chemical synthesis routes for the production of the active ingredient levetiracetam, a drug
