Master thesis
Evaluation of Aspergillus-specific aptamers
Starting date: August/September 2022; Duration: 6 months
The project
This thesis project focuses on the evaluation and use of DNA aptamers (short single-stranded oligonucleotides) for the recognition and binding of cells of the filamentous fungus Aspergillus niger. Aptamers specific to A. niger have the potential to be employed in diagnostic applications against aspergillosis.
By using state of the art techniques and instruments (e.g., qPCR, flow cytometry and cell sorting), you will test previously developed DNA aptamers for their capability to bind specifically to A. niger cells. In parallel, you will establish a method to evaluate fluorescent Aspergillus-specific aptamers based on the use of a fluorescence activated cell sorter (FACS).
Your profile:
- Bachelor degree in a relevant subject (e.g., molecular biology, biotechnology, microbiology)
- Highly motivated, communicative and eager to learn
- Previous experience with filamentous fungi and basic molecular biology techniques is a plus
- Good verbal and written communication skills in English (German not required)
Our offer:
- A stimulating and international scientific environment in the centre of Vienna
- Teamwork and guidance during the experiments and writing of the thesis
- 6-month employment (€ 469.67/month, 10 hours a week)
- Participation in weekly lab and team meetings
For any questions you can write to Valeria Ellena.
Of course, we welcome applicants of all sexes (f/m/x), backgrounds and ages.