NMR-based metabolomics


Understanding the intricacies of metabolite fingerprints, their variations and absolute concentrations is paramount for a diverse array of studies. This includes biomarker studies, mechanistic inquiries, metabolic engineering endeavors, or quality assessments of complex mixtures.


Metabolomics is a cornerstone in metabolism research, spans from organelles to human populations, and strives to decipher the molecular basis of biochemical processes. By leveraging Nuclear Magnetic Resonance (NMR) spectroscopy our approach allows for the elucidation of the metabolome – sum of the chemical fingerprints – enabling systemic conclusions about metabolic changes and disease trajectories.


Our offer revolves around NMR-based metabolomics, showcasing numerous advantages. These include:

  1. Absolute Quantification: Easier implementation of precise quantification
  2. Reduced ‘dark’ space: Minimization of unassigned features for enhanced data clarity
  3. Identification and Structure Determination: Ideal for yet unidentified metabolites.
  4. Isotope tracing: Straightforward implementation for deeper insights
  5. Easy sample preparation: User-friendly procedures
  6. Robustness: Ensuring reliable and consistent results
  7. Lipoprotein Detection and Quantification
  8. Cost-Effective: Lower costs for both sample preparation and measurements compared to mass spectrometry (metabolites) and analytical ultracentrifugation (lipoproteins)


Under protection of a CDA/NDA we provide you with professional strategies for untargeted or targeted profiling or quantification of metabolites (all matrices) and lipoproteins (human serum/plasma) from a plethora of matrices ranging from, but boing not limited to biofluids, tissues, cells, cell culture media, plant extracts, our other complex mixtures of small-molecules. IP developed in such a project would fully belong to our investor/industrial partner.


Univ. Prof. Dr. Tobias Madl, Dr. Hansjörg Habisch

Development status:

Technology Readiness Level 6 (Demonstrated in relevant environment)

Available for:

Joint Research Project, Contract Research


Can be generated for our industrial partners / investors


NMR spectroscopy, Metabolomics, Multivariate data analysis, Metabolite identification, Metabolite quantification, Bioinformatics, Omics, Biological samples, Clinical samples, Complex mixtures, Lipoproteins
Picture by Shutterstock

Dr. Martin U. Trinker
Director Business Development & Fundraising
Krenngasse 37
8010 Graz
+43 316 873 9316