Ene-reductases are the gold standard for alkene reduction in biocatalysis. However, their industrial implementation is hampered by their requirement for costly nicotinamide coenzymes. We aim to reduce these costs by smart enzyme engineering.

Helicobacter pylori and Campylobacter spp. are leading causes of gastrointestinal illness worldwide. Existing solutions are limited, and there’s a need for broad-spectrum protection. acib offers a dual-protection vaccine platform using H. pylori to deliver Campylobacter antigens, potentially reducing development time and costs for future multi-pathogen vaccines.

Are you grappling with challenges related to protein stability, activity, expression, or purification? Look no further – the Austrian Centre of Industrial Biotechnology (acib) offers new machine learning and neural network tools to predict better protein variants with unprecedented accuracy.

Uncertain about a (bio)plastic’s true sustainability? acib’s enzymatic degradation studies provide the answer you need. Let acib help you unveiling the fate of your (bio)polymer in various environments.

The global digestive health market is projected to reach EUR 90 billion by 2023. Existing treatments often have limitations. Milk extracellular vesicles (mEVs) offer a natural solution to promote gut health, strengthen protective barriers and reduce inflammation. acib can help you be the first to market this exciting technology.

The demand for sustainable and economically viable sources of pharmaceutical compounds is on the rise. Traditional methods rely heavily on petrochemicals, leading to environmental pollution and resource depletion. By utilizing lignin, a major component of biomass, as a starting material a greener approach to drug synthesis becomes possible.

Understanding molecular details of proteins is critical for sucessful drug discovery, protein engineering or formulation development. However, traditional techniques often struggle to capture the dynamic nature of proteins in solution. Let us help you overcome this challenge using HDX-MS!

Understanding molecular details of proteins is critical for sucessful drug discovery, protein engineering or formulation development. However, traditional techniques often struggle to capture the dynamic nature of proteins in solution. Let us help you overcome this challenge using HDX-MS!

Are you a pharmaceutical company struggling with high production costs for biopharmaceuticals due to limitations of CHO cell lines? Unleash the full potential of your CHO protein production with acib’s stabilizer technology to increase yields.

Did you know that phytosterols are natural compounds exhibiting a variety of health benefits for humans and pets? There is concern of not getting enough phytosterols from the diet, since the body can’t produce it on its own leading to elevated cholesterol levels, cardiovascular risks, limited protection against oxidative stress, and missed anti-inflammatory effects.

Did you know that the market for prebiotics is expected to increase by 11.3% per year until 2030? Health-conscious customers, as well as new applications in the feed industry are driving demand. With acib’s expertise on prebiotic bioproduction, companies can confidently venture into this lucrative market. Seize this opportunity!

Did you know that tire abrasion and washing of synthetic textiles are main contributors to microplastic pollution in the environment? There is an urgent need for bio-based and fully biodegradable alternatives. However, some features have been challenging to replace, such as the elasticity of some plastics. Discover how acib has found a solution that can also help combat climate change …

In view of the antibiotic resistance crisis, identifying new targets to establish robust intervention strategies is urgently needed. Targeting the shikimate pathway is a highly promising approach, as exemplified by the blockbuster herbicide glyphosate.

The reliable production of alkaloids, including the pain medication precursors (R)-reticuline and salutaridine promorphian, is absolutely critical for the pharmaceutical industry. However, traditional methods rely on plant extraction, leading to supply chain vulnerabilities.

Flavors and fragrances, cosmetics, lubricants, surfactants, pesticides, fine chemicals, bioplastics, biofuels, detergents, adhesives, solvents, dispersants for dyes, textile finishing – the potential applications of bio-based alkanes and alkenes seem almost endless. At acib, we provide the tools to make this vision a reality.

Yeast surface display represents a powerful protein lab)
engineering technology, enabling a wide range of applications including the generation of novel antigen binding sites (also in non-antibody proteins), affinity maturation, construction of pH-dependent binding sites and protein stabilization, among many others.

Cell-Free circulating DNA (cfDNA) is an incredible source of information on the health status of humans and animals. This largely untapped source of knowledge can be utilized to detect sepsis earlier than ever before and independent of the causing pathogen.

Ever wondered how to produce essential pharmaceuticals more affordably and sustainably? acib is going to revolutionize the production of plant-derived bioactive molecules by developing a plant cell-based, bioreactor-compatible technology to defeat the limitations of traditional manufacturing approaches. Check it out …

Understanding the intricacies of metabolite fingerprints, their variations and absolute concentrations is paramount for a diverse array of studies. This includes biomarker studies, mechanistic inquiries, metabolic engineering endeavors, or quality assessments of complex mixtures.

acib has spearheaded for over a decade an international collaborative effort to unlock the potential of CHO-cells, addressing the main challenges of cell-line optimization. Benefit from reduced time-to-market and lower production cost and let acib streamline your process!

Antibiotic resistance is growing worldwide, while consumers urgently demand antibiotic-free products… What if there would be a new tool to fight the danger of pathogens that is effective and environmentally friendly

Harnessing the huge potential of biotechnology for new, sustainable and cost-effective production of high-value cosmetic ingredients has become a reality.

The research field of polymer & environmental biotechnology focusses on the development of biotechnical and enzymatic strategies related to polymer / material processing and environmental aspects. The expertise ranges from function-based enzyme development, in silico screenings and enzyme activation to estimate the biodegradation and fermentation pilots.​

Did you know that food waste valorisation is currently at the centre of debates on the development of various “circular bioeconomy“ models? Fruit waste, in particular, represents an incredible sustainable and renewable reserve for the extraction and/or production of various products, which include well the production of biopolymers for food packaging.

3D-bioprinting is revolutionizing research and medicine by enabling the precise creation of intricate 3D structures using both living cells and biomaterials. Let acib help you capitalize on this technology to advance novel scaffolds, tissue engineering, drug testing and personalized medicine!

If life science would be a country, it would rank third in plastic waste production, and 5th in CO2 emission. We need to become more sustainable in terms of energy and plastic use. Sterilization before, and inactivation after use requires vast amounts of energy and water, while single use plastics are from petrochemical plastic and are incinerated after use.

Ginseng is among the most famous health-promoting plants in the world. But did you know that ginseng has a very high cost of production? acib is going to change that by developing an industrial yeast for ginsenoside production and is looking for interested companies!​

Did you know that cholesterol is absolutely vital for our cells and a very popular ingredient in a wide range of cosmetics? Did you also know that cholesterol is animal derived, and naturally produced vegan cholesterol is painfully missing on the market? Let’s change that with acib’s cholesterol-producing yeast!

Europe’s Green Deal largely depends on lithium imports, but there are environmental concerns against mining in Europe. What if there would be a green, environmentally-friendly ‘bio-mining’ alternative for Europe?