Rapid Test for Joint Infection
Bacterial joint infections are a devastating complication, causing pain, death, and costly treatments. While current diagnostics are either slow and unreliable or expensive and complex, acib’s Point-of-Care (POC) test provides fast, accurate results at low cost.
Novel Diagnostics for Aspergillosis
Tired of slow and inaccurate aspergillosis diagnostics? acib’s innovative DNA aptamer technology revolutionizes diagnostics with precision and speed.
Human Milk Oligosaccharides (HMOs)
Did you know that HMOs are not only important for healthy infant development, but can also serve as a prebiotic for adults, contribute to combating allergies and diabetes and enhance the effectiveness of vaccines and antibiotics? And did you know that the main reason they are not used more often is that they have been so hard to come by until now!
Affordable Biocatalysis: NADH-dependent Ene-reductases
Ene-reductases are the gold standard for alkene reduction in biocatalysis. However, their industrial implementation is hampered by their requirement for costly nicotinamide coenzymes. We aim to reduce these costs by smart enzyme engineering.
Helicobacter pylori vaccine platform
Helicobacter pylori and Campylobacter spp. are leading causes of gastrointestinal illness worldwide. Existing solutions are limited, and there’s a need for broad-spectrum protection. acib offers a dual-protection vaccine platform using H. pylori to deliver Campylobacter antigens, potentially reducing development time and costs for future multi-pathogen vaccines.
Protein Engineering Beyond Nature’s Limit
Are you grappling with challenges related to protein stability, activity, expression, or purification? Look no further – the Austrian Centre of Industrial Biotechnology (acib) offers new machine learning and neural network tools to predict better protein variants with unprecedented accuracy.
Enzymatic degradation studies for Polymers
Uncertain about a (bio)plastic’s true sustainability? acib’s enzymatic degradation studies provide the answer you need. Let acib help you unveiling the fate of your (bio)polymer in various environments.
Milk Extracellular Vesicles (mEVs) for digestive health
The global digestive health market is projected to reach EUR 90 billion by 2023. Existing treatments often have limitations. Milk extracellular vesicles (mEVs) offer a natural solution to promote gut health, strengthen protective barriers and reduce inflammation. acib can help you be the first to market this exciting technology.
Green Pharmaceuticals from Lignin
The demand for sustainable and economically viable sources of pharmaceutical compounds is on the rise. Traditional methods rely heavily on petrochemicals, leading to environmental pollution and resource depletion. By utilizing lignin, a major component of biomass, as a starting material a greener approach to drug synthesis becomes possible.
Deuterium Exchange (HDX) coupled to Mass Spectrometry (MS) analyses of protein structure/function
Understanding molecular details of proteins is critical for sucessful drug discovery, protein engineering or formulation development. However, traditional techniques often struggle to capture the dynamic nature of proteins in solution. Let us help you overcome this challenge using HDX-MS!
NMR-Based Process Analyses of Cell Culture Media in Recombinant Protein Production
Understanding molecular details of proteins is critical for sucessful drug discovery, protein engineering or formulation development. However, traditional techniques often struggle to capture the dynamic nature of proteins in solution. Let us help you overcome this challenge using HDX-MS!
Maximizing Performance of CHO cells
Are you a pharmaceutical company struggling with high production costs for biopharmaceuticals due to limitations of CHO cell lines? Unleash the full potential of your CHO protein production with acib’s stabilizer technology to increase yields.
Microbial Phytosterol Production
Did you know that phytosterols are natural compounds exhibiting a variety of health benefits for humans and pets? There is concern of not getting enough phytosterols from the diet, since the body can’t produce it on its own leading to elevated cholesterol levels, cardiovascular risks, limited protection against oxidative stress, and missed anti-inflammatory effects.
Prebiotics
Did you know that the market for prebiotics is expected to increase by 11.3% per year until 2030? Health-conscious customers, as well as new applications in the feed industry are driving demand. With acib’s expertise on prebiotic bioproduction, companies can confidently venture into this lucrative market. Seize this opportunity!
mcl-PHAs: Eco-Friendly Elastic Polymers
Did you know that tire abrasion and washing of synthetic textiles are main contributors to microplastic pollution in the environment? There is an urgent need for bio-based and fully biodegradable alternatives. However, some features have been challenging to replace, such as the elasticity of some plastics. Discover how acib has found a solution that can also help combat climate change …
Next-Gen Antibiotics Targeting the Shikimate Pathway
In view of the antibiotic resistance crisis, identifying new targets to establish robust intervention strategies is urgently needed. Targeting the shikimate pathway is a highly promising approach, as exemplified by the blockbuster herbicide glyphosate.
Chemo-enzymatic route to alkaloids
The reliable production of alkaloids, including the pain medication precursors (R)-reticuline and salutaridine promorphian, is absolutely critical for the pharmaceutical industry. However, traditional methods rely on plant extraction, leading to supply chain vulnerabilities.
Dissemination & Communication
You are doing great science in the field of industrial biotechnology – we make sure that the public will notice.
Bio-based alkanes/alkenes production
Flavors and fragrances, cosmetics, lubricants, surfactants, pesticides, fine chemicals, bioplastics, biofuels, detergents, adhesives, solvents, dispersants for dyes, textile finishing – the potential applications of bio-based alkanes and alkenes seem almost endless. At acib, we provide the tools to make this vision a reality.
Yeast surface display: High-end protein engineering
Yeast surface display represents a powerful protein lab)
engineering technology, enabling a wide range of applications including the generation of novel antigen binding sites (also in non-antibody proteins), affinity maturation, construction of pH-dependent binding sites and protein stabilization, among many others.
Pathogen independent Sepsis detection by host response
Cell-Free circulating DNA (cfDNA) is an incredible source of information on the health status of humans and animals. This largely untapped source of knowledge can be utilized to detect sepsis earlier than ever before and independent of the causing pathogen.
Cultured Meds: Next-Gen Pharma
Ever wondered how to produce essential pharmaceuticals more affordably and sustainably? acib is going to revolutionize the production of plant-derived bioactive molecules by developing a plant cell-based, bioreactor-compatible technology to defeat the limitations of traditional manufacturing approaches. Check it out …
NMR-based metabolomics
Understanding the intricacies of metabolite fingerprints, their variations and absolute concentrations is paramount for a diverse array of studies. This includes biomarker studies, mechanistic inquiries, metabolic engineering endeavors, or quality assessments of complex mixtures.
The CHO-cell technology advantage
acib has spearheaded for over a decade an international collaborative effort to unlock the potential of CHO-cells, addressing the main challenges of cell-line optimization. Benefit from reduced time-to-market and lower production cost and let acib streamline your process!
The use of Bacteriophages in modern Biotechnology
Antibiotic resistance is growing worldwide, while consumers urgently demand antibiotic-free products… What if there would be a new tool to fight the danger of pathogens that is effective and environmentally friendly
Biotechnology for better cosmetics
Harnessing the huge potential of biotechnology for new, sustainable and cost-effective production of high-value cosmetic ingredients has become a reality.
Enzyme discovery and development for polymer processing
The research field of polymer & environmental biotechnology focusses on the development of biotechnical and enzymatic strategies related to polymer / material processing and environmental aspects. The expertise ranges from function-based enzyme development, in silico screenings and enzyme activation to estimate the biodegradation and fermentation pilots.
Fruit peels waste valorization
Did you know that food waste valorisation is currently at the centre of debates on the development of various “circular bioeconomy“ models? Fruit waste, in particular, represents an incredible sustainable and renewable reserve for the extraction and/or production of various products, which include well the production of biopolymers for food packaging.
Advanced 3D-Bioprinting
3D-bioprinting is revolutionizing research and medicine by enabling the precise creation of intricate 3D structures using both living cells and biomaterials. Let acib help you capitalize on this technology to advance novel scaffolds, tissue engineering, drug testing and personalized medicine!
The Compostable Bioprocess
If life science would be a country, it would rank third in plastic waste production, and 5th in CO2 emission. We need to become more sustainable in terms of energy and plastic use. Sterilization before, and inactivation after use requires vast amounts of energy and water, while single use plastics are from petrochemical plastic and are incinerated after use.