Ever wondered how to produce essential pharmaceuticals more affordably and sustainably? acib is going to revolutionize the production of plant-derived bioactive molecules by developing a plant cell-based, bioreactor-compatible technology to defeat the limitations of traditional manufacturing approaches. Check it out …
Understanding the intricacies of metabolite fingerprints, their variations and absolute concentrations is paramount for a diverse array of studies. This includes biomarker studies, mechanistic inquiries, metabolic engineering endeavors, or quality assessments of complex mixtures.
acib has spearheaded for over a decade an international collaborative effort to unlock the potential of CHO-cells, addressing the main challenges of cell-line optimization. Benefit from reduced time-to-market and lower production cost and let acib streamline your process!
The research field of polymer & environmental biotechnology focusses on the development of biotechnical and enzymatic strategies related to polymer / material processing and environmental aspects. The expertise ranges from function-based enzyme development, in silico screenings and enzyme activation to estimate the biodegradation and fermentation pilots.
Did you know that food waste valorisation is currently at the centre of debates on the development of various “circular bioeconomy“ models? Fruit waste, in particular, represents an incredible sustainable and renewable reserve for the extraction and/or production of various products, which include well the production of biopolymers for food packaging.
3D-bioprinting is revolutionizing research and medicine by enabling the precise creation of intricate 3D structures using both living cells and biomaterials. Let acib help you capitalize on this technology to advance novel scaffolds, tissue engineering, drug testing and personalized medicine!
If life science would be a country, it would rank third in plastic waste production, and 5th in CO2 emission. We need to become more sustainable in terms of energy and plastic use. Sterilization before, and inactivation after use requires vast amounts of energy and water, while single use plastics are from petrochemical plastic and are incinerated after use.
Ginseng is among the most famous health-promoting plants in the world. But did you know that ginseng has a very high cost of production? acib is going to change that by developing an industrial yeast for ginsenoside production and is looking for interested companies!
Did you know that cholesterol is absolutely vital for our cells and a very popular ingredient in a wide range of cosmetics? Did you also know that cholesterol is animal derived, and naturally produced vegan cholesterol is painfully missing on the market? Let’s change that with acib’s cholesterol-producing yeast!
Did you know that C-nucleosides are essential constituents of modern mRNA vaccines? Were you aware that, up until now, there have been limited options for efficient chemical syntheses? acib changed all that with its recent work (published in Nat.Commun).
Carbon-carbon bonds ultimately made the emergence of life on earth possible, but they can also bring life to new reactions, leading to many valuable molecules…Let us show you, what they can do!
Glutathione (γ-L-glutamyl-L-cysteinyl-glycine) is the main endogenous, cellular, thiol-based antioxidant existing in reduced (GSH) and oxidized (GSSG) forms. In healthy cells, the ratio of GSH:GSSG is actively kept higher than 100:1 but different stress-conditions can affect this balance thus it can be used as a readout of cellular redox state.
Knowledge of key biosynthetic steps and bottlenecks is a prerequisite for effective metabolic engineering of production strains. Not only the immediate biosynthetic precursors but also the general energetic and oxidative state of the production host can significantly influence achievable yields and quality of bioproducts.
LC – MS (/MS) analysis is the method of choice for proteomics. We use high resolution mass spectrometers to identify and relatively quantify thousands of proteins and their modification(s) and then perform statistic and bioinformatic analyses to determine differentially regulated proteins and pathways.
GFGG (Growth Factors Go Green), plant-based growth factor expression system for cultivated meat and pharma.
Growth factors are essential components in cell culture medium for pharmacological products as well as for cultivated meat production and also pharmaceuticals on their own. Still, their application is hampered by their folding instability.
You want to save money on expensive fermentation processes and speed them up? Young and viable cells provide a better fermentation performance. acib’s technology rejuvenates your yeast culture to increase process productivity withouth affecting other parameters.
Immune evasion is a hallmark of cancer, contributing signifcantly to the progression of malignancies and associated mortalities. An interdisciplinary approach lead by acib can assess personalized treatment options for patients, as well as lay the foundation to designing novel treatments.
You want healthy drinks with all the valuable ingredients and a good taste, but without or at least with less sugar? The good news is: You are not alone! The bad news is: It’s difficult to achieve with current technologies … Let’s develop some better ones!
acib’s vision is a world without suffering and with affordable access to food and medicine for all the people on this world. acib’s mission is to enable cost-effective and environmentally friendly new processes and products through the development of new technologies.
Coating proteins are part of the extracellular matrix (ECM) and are widely used in the pharmaceutical industry, medicine, and research to improve the adhesion of mammalian cells to surfaces/tissues in vivo and in vitro. Of the several hundred ECM proteins, only a few proteins are widely used for coating, with little research into their optimization.
Are you looking for an eco-friendly approach to improve the functionality of your product? Or do you want to integrate a renewable bioresource into your production pipeline and increase its sustainability? Microalgae could be your solution.
There are compounds so stable and inert that their potential for innovation and industrial applications seemed endless … and they have been produced in huge amounts. Their global accumulation in both environments, wildlife and humans, however, have lots of detrimental effects, but since they are so stable, there is nothing that we can do – or is there?