acib has an expert structural biology group, conducting protein X-ray crystallography and cryo-electron microscopy (cryo-EM) on proteins and protein-ligand complexes of interest. Depending on the method individual steps include initial protein crystallization trials, crystallization optimization, grid screening data collection, data processing, and structure solution.
In case similar protein models are available computer modelling can be performed to quickly yield homology based models for your R&D. In combination with our capabilities in molecular dynamics and docking simulations the interaction between your protein of choice and any compound/ligand can be further investigated.
In collaboration with the acib-spin off Innophore advanced algorithms can perform structure-based protein searches based on physico-chemical structural properties (independent of protein sequences) to identify suitable proteins for biotechnological or medical applications.