The concept includes composting the biomass used for biotechnological production (CHO, HEK, Vero, Yeast, etc.) after any secondary products, e.g. proteins, have been extracted, ensuring degradation of residual DNA as demonstrated for transgenic plants. Poly-lactic-acid can be used as a biodegradable building material for bioreactors and other equipment as we have previously shown. The added benefit is: 3D-printing can be developed to sterilize the material during the printing process avoiding sterilization in an R&D context. Accordingly, energy consumption can be reduced by >90% and the entire single-use bioprocesses can be set up in a bio-sourced and biodegradable manner, complying with the requirements of a circular economy.