The volatility and reactivity of aldehydes is a curse because their synthesis is challenging and a blessing: Aldehydes are applied as flavours and fragrances due to their volatility and characteristic olfactory properties. Aldehydes can undergo chemical transformations to numerous other functional groups. In short, the aldehyde is an invaluable chemical handle to make all sorts of products.
Nature is equipped with a portfolio of proteins with enzymatic activity to transform various precursor molecules to the respective aldehydes.
We are strong in the discovery of novel enzymes, the optimization of expression and reaction engineering. In case the enzyme is not good enough for your purpose, we improve it by using customized high-throughput screening methodology. We also develop sophisticated enzymatic cascades and/or integrate the biocatalysts into suitable hosts for whole-cell biotransformations.
Experts:Dr. Margit Winkler, Prof. Florian Rudroff, Dr. Christoph Winkler, Prof. Wolfgang Kroutil
Available for:Investments, Joint Research Projects, Contract Research, Joint Applications for public funding
Status of the project proposal:Technology Readiness Level 2-4
Keywords:Aldehyde, Flavour & Fragrance, Enzyme collections, Biocatalytic Synthesis, Enzyme engineering, Enzyme discovery
Picture credits: Pixabay