Qualitative LC – MS (/MS) analysis is the method of choice for quality control of proteins. We use high resolution mass spectrometers to identify intact protein masses and peptide fragment fingerprints to determine the amino acid sequence and its modification(s).
Carbon-carbon bonds ultimately made the emergence of life on earth possible, but they can also bring life to new reactions, leading to many valuable molecules…Let us show you, what they can do!
Glutathione (γ-L-glutamyl-L-cysteinyl-glycine) is the main endogenous, cellular, thiol-based antioxidant existing in reduced (GSH) and oxidized (GSSG) forms. In healthy cells, the ratio of GSH:GSSG is actively kept higher than 100:1 but different stress-conditions can affect this balance thus it can be used as a readout of cellular redox state.
Knowledge of key biosynthetic steps and bottlenecks is a prerequisite for effective metabolic engineering of production strains. Not only the immediate biosynthetic precursors but also the general energetic and oxidative state of the production host can significantly influence achievable yields and quality of bioproducts.
LC – MS (/MS) analysis is the method of choice for proteomics. We use high resolution mass spectrometers to identify and relatively quantify thousands of proteins and their modification(s) and then perform statistic and bioinformatic analyses to determine differentially regulated proteins and pathways.
Compact advanced training for biopharma with laboratory training for employees of pharmaceutical companies without relevant biotechnology training
As secondary metabolites are produced with the purpose to confer a selective advantage of the host organism they are an excellent source of novel bioactive compounds with great therapeutic potential for e.g. anti-biotics, anti-viral drugs and biological fungicides.
Growth factors are essential components in cell culture medium for pharmacological products as well as for cultivated meat production and also pharmaceuticals on their own. Still, their application is hampered by their folding instability.
You want to save money on expensive fermentation processes and speed them up? Young and viable cells provide a better fermentation performance. acib’s technology rejuvenates your yeast culture to increase process productivity withouth affecting other parameters.
Immune evasion is a hallmark of cancer, contributing signifcantly to the progression of malignancies and associated mortalities. An interdisciplinary approach lead by acib can assess personalized treatment options for patients, as well as lay the foundation to designing novel treatments.
